Your resume has to demonstrate your skills, experience and accomplishments.
Make sure to highlight any awards you have won and professional associations you are a part of.
Emphasize any technology skills you have. Sometimes employers worry that older workers may not be as current with technological advances. If you have skills in this area, make sure to mention them, especially relevant recent training.
Put your education listing toward the end of the resume since this is not the part you are trying to emphasize. Instead, list all of your experience first and highlight your expertise, awards and accomplishments. Make sure they know what your strongest credentials are.
If you are pursuing a degree, you can note the schools and years you have attended or classes you have taken. Some experts suggest that by noting "bachelor's degree not yet completed," your resume may make it past the Applicant Tracking System software that many companies use when screening applicants.
Note any training, certifications, continuing education, licenses, internal company courses, online training, seminars, workshops, etc., you have received in order to highlight all you have done to show you have successfully invested in your profession. You can list this under a professional development section of your resume.
While you may not have the college degree qualification for a job, you might have a long work history that you can highlight to potential employers. This will be especially beneficial to illustrate if you can show a pattern of career progression (moving up the ladder with increasingly greater responsibilities). If you can explain why you received more challenging assignments or positions, this might persuade potential employers that you do bring a lot to the table.
Follow up on resumes you submit. Having a personal connection with employers is a much stronger way of standing out among other applicants.